Some mechanisms of modeling the hydrostatic component of hemodynamics in microgravity
Baranov, V.M.; Tikhonov, M.A.; Kotov, A.N.; Kolesnikov, V.I.
Aviakosmicheskaia i Ekologicheskaia Meditsina 34(4): 27-31
2000
ISSN/ISBN: 0233-528X PMID: 11186580 Document Number: 513953
Proposed is a modified method to counteract the headword redistribution of local blood volumes in microgravity by discrete or combined exposure to respiration at negative pressure (RNP) and lower body negative pressure (LBNP). Physically and physiologically substantiated levels of the barometric influences on the central and peripheral hemodynamics to approximate the normal gradients of blood hydrostatic pressure along the body axis are given. Discrete RNP applied to test-subjects during HDT was shown to return the cerebral and cervical hemodynamic parameters to levels determined in horizontal position. Combination of RNP and LBNP had additive character as it advantaged the recovery of values characteristic of the orthostatic position. There are technical possibilities to integrate the LBNP and RNP devices for the benefit of scientific, certification, predictive, and training objectives of space biomedicine.