Removal of Foscarnet by hemodialysis using dialysate-side values
Sam, R.; Patel, S.B.; Popli, A.; Leehey, D.J.; Gambertoglio, J.G.; Ing, T.S.
International Journal of Artificial Organs 23(3): 165-167
2000
ISSN/ISBN: 0391-3988 PMID: 10795660 Document Number: 513226
Foscarnet is an antiviral agent widely used in the treatment of cytomegalovirus (CMV) infection. We describe a cardiac transplant patient, who while being maintained with hemodialysis because of tobramycin-induced acute renal failure, was given Foscarnet for disseminated CMV infection. Using dialysate-side clearance methodology, we found the dialyzer clearance of Foscarnet to be in the order of 89 ml/min.