Lipoprotein (a) status in coronary heart disease
Khan, M.A.; Baseer, A.
Jpma. Journal of the Pakistan Medical Association 50(2): 47-50
2000
ISSN/ISBN: 0030-9982 PMID: 10769521 Document Number: 513212
Objective: To compare the magnitude of lipid, and lipoproteins, especially the lipoprotein(a) (Lp(a)), in controls and patients with coronary heart disease (CHD). Methods: Serum total cholesterol, triglyceride, HDL-C, LDL-C, VLDL-C, apo A1, apo B, and Lp(a) levels were determined in 37 patients with CHD and 25 age matched control subjects. Results: A significant difference (P<0.001) in lipid and apolipoprotein ratios were found. Lp(a) and other lipid parameters were found significantly high (P<0.001) with the exception of HDL-C and apo B which were significantly low (P<0.001) in CHD patients. Conclusions: Elevated levels of Lp(a) suggest not only its role in atherogenesis, leading to CHD, but also that Lp(a) should be given due consideration while assessing CHD risk.