Cholesterol and lipoprotein (a) as risk factors for coronary heart disease in elderly subjects
Stober, C.; Clarke, A.; Mulvaney, A.; Harland, J.; Neithercut, W.D.
British Journal of Biomedical Science 51(2): 114-118
1994
ISSN/ISBN: 0967-4845 PMID: 8049607 Document Number: 422866
Lipoprotein (a) concentrations were measured in serum samples from healthy volunteers, individuals with premature coronary artery disease, individuals with hyperlipaemia but without evidence of premature coronary artery disease, and in elderly men and women who had hyperlipaemia. Concentrations in individuals with premature coronary artery disease were the same as those in healthy volunteers, while in both these groups they were lower than those found in hyperlipaemic elderly men and women, and those found in hyperlipaemic women 36-68 years old. No association between increased lipoprotein(a) concentration and mortality as a result of premature coronary artery disease was demonstrated. Increased lipoprotein(a) levels found in the hyperlipaemic individuals also suggested that it may not be an independent risk factor.