Recurrence of rapidly progressive glomerulonephritis probably associated with two different kinds of drugs
Aoki, S.; Kotooka, N.; Yokoyama, M.; Ikeda, Y.; Tomiyoshi, Y.; Sakemi, T.; Yonemitsu, N.
Clinical Nephrology 54(3): 249-251
2000
ISSN/ISBN: 0301-0430 PMID: 11020025 Document Number: 512641
We describe a rare case that developed a rapidly progressive glomerulonephritis twice in a 69-year-old man during a course of treatment, first with allopurinol and then with piperacillin. The cessation of each treatment was followed by spontaneous recovery in renal function. A renal biopsy showed crescentic glomerulonephritis with mild tubulointerstitial change and a skin biopsy showed leukocytoclastic vasculitis. This is, to our knowledge, a very rare case of crescentic glomerulonephritis, probably associated with vasculitis during a course of treatment with two different kinds of drugs.