Comparison of two serotype 1 MDV isolates
Miles, A.M.; Anderson, A.S.; Bernberg, E.L.; Kent, J.; Rosenberger, J.K.; Pope, C.R.; Morgan, R.W.
Acta Virologica 43(2-3): 102-105
1999
ISSN/ISBN: 0001-723X PMID: 10696428 Document Number: 511373
We compared the RB1B and T. King (TK) serotype 1 isolates of Marek's disease virus (MDV) in vivo. Body and organ weights, mortality, and lesions indicated that the TK inoculum established early infection more efficiently than RB1B and did greater damage to the bursa of Fabricius and thymus. Subsequent studies showed that the TK inoculum that we used contained chicken infectious anemia virus (CIAV). Therefore, pathogenicity profiles shown here should be interpreted with the presence of CIAV contamination in the TK stock in mind.
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