Cutaneous signs of selected systemic diseases
Kihiczak, N.I.; Leevy, C.B.; Krysicki, M.M.; Janniger, C.K.; Schneider, I.; Shriner, D.L.; Lambert, W.C.; Schwartz, R.A.
Journal of Medicine 30(1-2): 3-12
1999
ISSN/ISBN: 0025-7850 PMID: 10515235 Document Number: 510997
In this work we will discuss three cutaneous markers of systemic disease. Acanthosis nigricans is the most widely known in this category. Cutaneous angiokeratomas are usually associated with enzyme defect disorders, such as Fabry's disease, and are linked in this work as a reactive pattern in hepatorenal failure. Mast cell disease may occur in a number of forms, often with systemic involvement.