Experimental study of radiosensitization of buthionine sulffoximine (BSO) on Acc-2 transplanted tumor
Wan, G.Y.; Lin, G.C.; Wang, Z.H.; Chen, W.T.
Shanghai Kou Qiang Yi Xue 8(1): 4-6
1999
ISSN/ISBN: 1006-7248 PMID: 15048302 Document Number: 509116
OBJECTIVE:The effect of radiosensitization of BSO on Acc-2 transplanted tumor was studied in vivo.METHODS: There were four groups in this experiment:control group,radiation group and BSO+radiation group.The drug dose of BSO is 5mmol/kg and the radiation dose was 10Gy. RESULTS:The result demonstrated that the tumor inhibitive rate was 8.5%,12.6% and 45.37% respectively compared with control group. CONCLUSION: BSO has radiosensitizative effect on Acc-2 transplanted tumor.