A testicular tumor with features of a sex cord tumor with annular tubules and calcified large-cell Sertoli tumor
Zámecník, M.; Sedlácek, P.; Gogora, M.; Mukensnábl, P.
Ceskoslovenska Patologie 35(1): 20-23
1999
ISSN/ISBN: 1210-7875 PMID: 10379059 Document Number: 509008
An unusual testicular tumour with features of both sex cord tumour with annular tubules and large-cell calcifying Sertoli cell tumour is described. The tumour occurred in a 20-year-old man in the left testis as a 1 cm-measuring well circumscribed solitary lesion. Histologically, it showed sertoliform annular tubules with included eosinophilic nodules as well as isolated large cells and cords to sheets of the cells lying in a sclerosing stroma. A few psammomatous microcalcifications were seen. In contrast to similar cases reported before, the patient did not have any signs of Peutz-Jeghers syndrome, feminization or other complex dysplastic syndromes. The case indicates that tumours of this type may occur in phenotypically normal patients like pure large cell calcifying Sertoli cell tumours or ovarian sex-cord tumours with annular tubules. It further supports a close histogenetic relationship between these two entities.