HLA-DMA and HLA-DMB genotyping in patients with rheumatic diseases

Yen, J.H.; Tsai, W.C.; Tsai, J.J.; Chen, C.J.; Lin, C.H.; Ou, T.T.; Wu, C.C.; Liu, H.W.; Yen, J.H; Tsai, W.C; Tsai, J.J; Chen, C.J; Lin, C.H; Ou, T.T; Wu, C.C; Liu, H.W

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HLA-DMA and HLA-DMB genotyping in patients with rheumatic diseases

Yen, J.H.; Tsai, W.C.; Tsai, J.J.; Chen, C.J.; Lin, C.H.; Ou, T.T.; Wu, C.C.; Liu, H.W.

Kaohsiung Journal of Medical Sciences 15(5): 263-267

1999

ISSN/ISBN: 1607-551X

PMID: 10375868

Document Number: 508369

To investigate the correlation of HLA-DMA and DMB alleles to some rheumatic diseases, HLA-DMA and DMB genes were detected in 11 patients with juvenile rheumatoid arthritis (JRA), 22 patients with psoriatic arthritis, 26 patients with Behcet's disease, 62 patients with ankylosing spondylitis (AS), and 138 unrelated healthy controls. There was no significant difference in phenotypic frequencies of HLA-DMA and DMB alleles between controls and patients with these rheumatic diseases. HLA-DMA and DMB genes are not related to the susceptibility of JRA, psoriatic arthritis, Behcet's disease, and AS.