Hypolipidemic action of ascofuranone in hepatoblastoma G2 cell culture
Trenin, A.S.
Antibiotiki i Khimioterapiia 44(9): 7-9
1999
ISSN/ISBN: 0235-2990 PMID: 10511901 Document Number: 507345
Ascofuranone, an isoprenoid antibiotic, suppressed 14C acetate incorporation into cholesterol, cholesterol ethers, triglycerides, phospholipids and free fatty acids in Hep G2 cell culture. Such a complex action of the antibiotic on lipid synthesis and metabolism was not connected with the inhibition of protein synthesis and the antibiotic toxicity.
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