Quantitative collagen as a golden standard in differential diagnosing of fibrotic changes in liver tissue
Jonsson, J.; Babic, A.
Studies in Health Technology and Informatics 68: 749-754
1999
ISSN/ISBN: 0926-9630 PMID: 10724994 Document Number: 506475
Determining a presence and degree of liver fibrosis provides means for diagnosing disease related processes. We have used two data mining methods, discriminant and regression analyses, to acquire knowledge from the data of 211 patients. We have shown and discussed that quantitative collagen has a distinguished discriminating power and can serve as a golden standard. We have additionally succeeded to obtain a formula consisting of standardised blood tests that can replace quantitative collagen. Practical implications of this is a non-invasive and cost efficient patient examination. All the results are now left for clinical evaluation and so is the current way of histopathological classifications.