Thrombotic thrombocytopenic purpura as an initial presentation of limited systemic sclerosis
Towheed, T.E.; Anastassiades, T.P.; Ford, S.E.; Ford, P.M.; Lee, P.
Journal of Rheumatology 26(7): 1613-1616
1999
ISSN/ISBN: 0315-162X PMID: 10405954 Document Number: 506056
Thrombotic thrombocytopenic purpura (TTP) is a rare complication of scleroderma (systemic sclerosis, SSc). In the 5 reports documenting the association of TTP and SSc, the TTP syndrome developed on a background of well established SSc. We describe a 51-year-old woman with a 5 month history of an evolving connective tissue disease syndrome who presented initially with TTP, followed 4 months later by limited cutaneous SSc and Raynaud's phenomenon.