A statistical evaluation of the Youden Matched-Pairs Procedure

McClure, F.D.

Journal - Association of Official Analytical Chemists 82(2): 375-383

1999


ISSN/ISBN: 0004-5756
PMID: 10191544
Document Number: 505814
AOAC INTERNATIONAL currently permits investigators to use the Youden Matched-Pairs Procedure to obtain estimates of the method performance indicators repeatability and reproducibility (S(r) and SR, respectively). This report explains the statistical model assumptions upon which the procedure is based, provides validity tests for several of these assumptions, explains conditions under which Youdens' "precision error" is not consistent with precision estimate S(r) or SR as defined by AOAC INTERNATIONAL, and indicates when precision estimates based on the procedure should be interpreted with caution or should not be used.

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