Effects of monoclonal antibody against the major cell surface protein on salivary agglutinin mediated aggregation of Streptococcus sobrinus
Zhang, P.; Fan, M.; Bian, Z.
Hua Xi Kou Qiang Yi Xue Za Zhi 17(3): 221-223
1999
ISSN/ISBN: 1000-1182 PMID: 12539288 Document Number: 505551
To investigate the effects of monoclonal antibody on salivary agglutinin-mediated aggregation of Streptococcus sobrinus in vitro. Bacterial aggregation inhibition was measured under OD650 at 10 minutes intervals for 1 hour. It showed that the McAb ZS2/286 raised against the PAg of S. sobrinus 6715 could inhibit the aggregation by some degree, but the effect was not significant. The McAb ZS2/286 might not bind directly to the functionally important region of PAg related to aggregation.
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