Immunomodulator Cycloferon in the comprehensive treatment of patients with acute non-lymphoblastic leukemia
Moiseev, S.I.; Abdulkadyrov, K.M.; Bubnova, L.N.; Glazanova, T.V.; Rozanova, O.E.; Pavlova, I.E.; Balashova, V.A.; Kovalenko, A.L.
Voprosy Onkologii 45(4): 405-410
1999
ISSN/ISBN: 0507-3758 PMID: 10532100 Document Number: 504554
The therapeutic benefit and action of the immunomodulator Cycloferon were evaluated in patients with acute non-lymphoblastic leukemia. When administered in conjunction with chemotherapy during first complete remission, it reduced both early-onset relapse frequency and degree of cytostatic-induced immune deficiency. The drug's action is mediated by changes taking place in cytokine and interferon synthesis.