Induction of osteointegration of rabbit mandibular central fissure with guided tissue regeneration
Xu, X.; Yang, P.S.; Ma, Y.; Sun, S.Z.; Li, Q.; Wang, J.T.
Shanghai Kou Qiang Yi Xue 8(4): 193-194
1999
ISSN/ISBN: 1006-7248 PMID: 15048205 Document Number: 504421
OBJECTIVE:To observe the effect of guided tissue regeneration (GTR) on induction of ostegenesis in developmental bone clefts,and provide a basis for the use of GTR to repair bony clefts in cleft lip and palate patients.METHODS:The e-PTFE membrane was placed on the labial and lingual sides of the rabbit mandibular central fissure.A radiological and pathological study was performed to determine the healing of the fissure integration.RESULTS:The results showed that the bony cleft was completely integrated 4 weeks after placement of the barrier membrane.CONCLUSION:GTR is an effective approach to reconstruct bony cleft,and is likely to be used in repair of alveolar cleft and cleft palate.