Benoxaprofen: once a day vs twice a day in patients with rheumatoid arthritis or osteoarthritis
Roth, S.H.
Journal of Rheumatology. Suppl 6: 68-75
1980
ISSN/ISBN: 0380-0903 PMID: 6993675 Document Number: 5033
This multicenter clinical trial was conducted in patients with rheumatoid arthritis and osteoarthritis in an effort to evaluate and compare the efficacy and safety of benoxaprofen when taken as a single 600 mg dose in the evening or when taken in 2 300 mg doses. The results of the double-blind crossover studies demonstrated the effectiveness of the qd and bid dose and revealed no significant difference between the 2 dose regimens. They also showed the once-daily dose, a dose that is more convenient and easier to comply with, to be as effective as the twice-daily dose.
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