Vascular reactivity and thrombus formation during postischemic reperfusion
Vlasov, T.D.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 85(11): 1391-1395
1999
ISSN/ISBN: 0869-8139 PMID: 10687171 Document Number: 502344
Reactivity, thrombogeneity, and thromboresistance of the rat mesentery microvessels were studied in postischemic reperfusion of the intestine, the brain, an extremity. Irrespective of ischemia localisation, an augmentation of the microvessels reactivity and reduction of their thromboresistance, were found. The microvessels thrombogeneity was depended on the ischemia localisation: an augmentation of the thrombogenity occurred in arterioles whereas it was reduced in venules following the brain and intestine reperfusion. A possible mechanism of the phenomenon may involve a deficiency of the nitric oxide synthesis.