Lipid metabolism of the heart in ischemia and postischemic reperfusion
Toleĭkis, A.I.; Dagis, A.I.; Trumpitskas, A.I.; Prashkiavichius, A.K.
Voprosy Meditsinskoi Khimii 31(2): 102-105
1985
ISSN/ISBN: 0042-8809 PMID: 4002648 Document Number: 253767
Content of unesterified fatty acids (FFA), phospholipids and triglycerides was studied in myocardium of control rabbits, of rabbits with ischemia (1 hr and 4 hrs) of myocardium and in postischemic reperfusion. In the ischemic myocardium content of phospholipids was gradually decreased; FFA increased within the first hour of ischemia. In reperfusion and prolongation of ischemia up to 4 hrs FFA were not altered. The data obtained suggest that a decrease in the ratio between the rates of FFA consumption and of lipid hydrolysis was responsible for an increase in the FFA content and in the phospholipid concentration.