The coagulogram characteristics of patients with non-insulin-dependent diabetes mellitus
Harbarchuk, O.I.
Likars'ka Sprava 1: 62-64
1999
ISSN/ISBN: 1019-5297 PMID: 10424001 Document Number: 501606
NIDDM patients were studied for the condition of their system of hemostasis as related to the presence of diabetes-associated abnormalities of the nervous and vascular systems. The hemostasis system undergoes unequal changes that appeared to be related to the presence and degree of complications. In the absence of apparent clinical manifestations of diabetes complications the above-named system is in the state of either normo- or hypofunction. Moderate severity neuro- and angiopathies present with hypercoagulation with concomitant decline in the reaction of fibrinolysis. In those instances in which the patient's condition is very serious, with grave forms of diabetic foot, depression of processes of fibrinolysis is being maintained with concurrent development of manifest phenomena of hypocoagulation, which fact cast doubt on the expediency of employment of anticoagulants.