Neurophysiological correlates of delayed visual differentiation in monkeys: effect of location of the NMDA-receptor intracortical blockade
Dudkin, K.N.; Kruchinin, V.K.; Chueva, I.V.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 85(12): 1465-1479
1999
ISSN/ISBN: 0869-8139 PMID: 10687181 Document Number: 499839
A multi-factor variance analysis revealed that the 2-amino-5-phosphonovalerian acid (APV) effect was manifested in monkeys by a decrease in the number of correct responses entailing a two-fold shortening of the short-term information storage, as well as by an augmentation of the motor responses' time. The correct responses' probability depended on the APV diffusion localisation in the cortex whereas the motor responses' time did not depend on it. The APV effect was accompanied by a desynchronisation of the unit activity in fields 46 and 17. Neurophysiological correlates of cognitive functions, are discussed.