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Congenital afibrinogenemia in Hasan Sadikin Hospital

Supandiman, I.; Sumantri, R.

Southeast Asian Journal of Tropical Medicine and Public Health 24(Suppl 1): 267-269

1993

ISSN/ISBN: 0125-1562
PMID: 7886594
Document Number: 498980
A case of a 24-year-old male with congenital afibrinogenemia has been discussed. The diagnosis was made based upon history, physical examination, umbilical cord bleeding, bleeding history and similar cases were found being the patient's grandfather and brother. Laboratory tests supported the diagnosis with a prolonged bleeding time, prothrombin time (PT), undetected partial thromboplastin time (PTT), flat line on thromboelastogram, and undetected fibrinogen (less than 78 mg/dl), with substitution test which showed fibrinogen deficiency.

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