Nasal airflow in growth hormone treatment
Ellegård, E.; Ellegård, L.
Rhinology 36(2): 66-68
1998
ISSN/ISBN: 0300-0729 PMID: 9695160 Document Number: 497794
Nasal congestion due to hormonal influences has been recognized as a clinical entity, and a "hormonal rhinitis" has been proposed to occur in acromegaly. In this study we investigated the effect of low-dose recombinant human growth hormone over eight weeks on nasal congestion as measured by nasal peak flow in a randomized, placebo-controlled, double-blind crossover clinical trial in ten patients with short bowel syndrome. The treatment did not induce a significant nasal congestion. Whether higher doses as used in many catabolic conditions do remains to be determined.