Sorption of non-narcotic analgetic drugs of medicinal charcoal
Sobczak, H.; Pawlaczyk, J.
Acta Poloniae Pharmaceutica 55(4): 279-283
1998
ISSN/ISBN: 0001-6837 PMID: 9821393 Document Number: 497707
Adsorption of four 5-pyrazolone derivatives and two carboxylic acids from aqueous solutions was studied. Partition coefficients for the analyzed drugs were calculated. Good corelation between log(k1, k2) (Langmuir constants) and log (octanol-water partition coefficient) of the drugs were found. The higher log(k1k2) value the higher solubility of the non-narcotic and analgetic drugs.
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