Thyroid volume is progressively reduced as a sequela of neck irradiation for childhood Hodgkin's disease
Bossi, G.; Larizza, D.; Sommaruga, G.; Corbella, F.; Klersy, C.; Aricò, M.
Haematologica 83(8): 754-756
1998
ISSN/ISBN: 0390-6078 PMID: 9793265 Document Number: 497588
Thyroid volume reduction was observed, among 25 subjects off-therapy after Hodgkin's disease. The volume reduction was related to dose (p = 0.014) and time from radiotherapy (p = 0.01). The correlation was very specific since all patients with reduced volume had hypothyroidism, but not very sensitive since 25% of subjects with thyroid dysfunction had normal gland volume.
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