Ophthalmopathy after neck irradiation therapy for Hodgkin's disease
Jackson, R.; Rosenberg, C.; Kleinmann, R.; Vagenakis, A.G.; Braverman, L.E.
Cancer Treatment Reports 63(8): 1393-1395
1979
ISSN/ISBN: 0361-5960 PMID: 582577 Document Number: 144360
Ophthalmopathy associated with autoimmune thyroid disease (Graves' ophthalmopathy) may occur years after irradiation of the neck for nonthyroid malignant disease. Two patients developed this complication 2 and 18 years after irradiation treatment of Hodgkin's disease: one with hypothyroidism associated with Hashimoto's thyroiditis and the other with hyperthyroidism. Careful long-term observation of thyroid function following neck irradiation is recommended in view of this unusual complication and the frequent occurrence of hypothyroidism.