Malignant mixed mullerian tumours of the body of the uterus: a clinicopathological study of 20 cases
Muthuphei, M.N.; Maluleke, H.J.
Central African Journal of Medicine 44(2): 45-47
1998
ISSN/ISBN: 0008-9176 PMID: 9675973 Document Number: 497035
Objective: To review the clinical and histopathological data on malignant mixed muellerian tumours . Design: A retrospective study of 20 cases of malignant mixed muellerian tumours seen over a period of five and half years. Setting: Departments of Obstetrics and Gynaecology and Anatomical Pathology at Garankuwa Academic Hospital. Subjects: Clinical and histopathological records of patients with malignant mixed muellerian tumours of the body of the uterus. Methods: Clinical record and histopathological slides were reviewed. Age, clinical presentation and histological appearances of the cases were noted. Results: The patient age ranged from 16 to 78 years with a median of 63 years (Q1 = 58.5, Q3 = 71.5). Of the 20 cases 14 died within 12 months of diagnosis. Clinical staging and histological staging had no effect on tumour behaviour and outcome of disease. Conclusion: Malignant mixed muellerian tumours are predominantly seen in post menopausal women. These tumours have a very poor prognosis irrespective of clinic stage, histological grade or the type of the stroma.