Effects of preeclampsia and eclampsia on cord blood coagulation tests
Djelmis, J.; Buković, D.; Ivanisević, M.; Kovacević, V.; Pfeifer, D.
Collegium Antropologicum 22(1): 113-117
1998
ISSN/ISBN: 0350-6134 PMID: 10097426 Document Number: 494723
Blood coagulation tests were determined in fifty-three paired umbilical cord blood and maternal venous blood samples originating from term singleton vaginal cephalic deliveries. The index group comprised seventeen deliveries complicated by preeclampsia or eclampsia, and the control group comprised thirty-six healthy women with uneventful pregnancies and deliveries. Mean values obtained from the coagulation and fibrinolytic assays did not significantly differ between study groups, except for antithrombin III levels in index group of neonates, which were significantly lower. Comparison of coagulation and fibrinolytic characteristics between mothers and their neonates produced expected level of difference due to immaturity of their haemostatic mechanisms. We found alterations in maternal blood coagulation and fibrinolysis and evidence of increased intravascular coagulation with severe preeclampsia and IUGR.