Experimental model of subfebrile condition of central origin
Semenia, I.N.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 84(12): 1428-1431
1998
ISSN/ISBN: 0869-8139 PMID: 10204190 Document Number: 494479
Central model of subfebrility was experimentally developed using administration of fresh homologous blood from an unanesthetised donor into the rat brain lateral ventricle. Rectal temperature significantly increased by the end of the 1st day of the administration. Duration of the hyperthermic response was about 8 days. The body temperature rise varied from 0.45 to 0.7 degrees C. The central subfebrility had no initial fenrile phase. An increased level of glucose in the blood serum during central subfebrility suggests an altered activity of the sympathetic nervous system to be one of the causes of the subfebrility development.