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Feasibility study of laser-induced fluorescence (LIF) spectrum for diagnosis of colon cancer

Zhai, L.; Li, S.; Gao, G.

Zhonghua Zhong Liu Za Zhi 20(1): 76-77

1998

ISSN/ISBN: 0253-3766
PMID: 10921068
Document Number: 494340
To study the usefulness of laser-induced fluorescence (LIF) spectrum for diagnosis of colon cancer. Nitrogen laser, wavelength 337 nm, optical multichannel analyzer (OMA III) were used to demonstrate LIF spectra. A standard spectrum of LIF of colon cancer was used to analyse that of 51 surgically removed colon specimens and the results were compared with pathological findings. Compared with pathological findings, LIF spectrum examination had 80.0% sensitivity, 100% specificity, with positive predictive value of 100%, negative predictive value of 83.9% and accuracy of 90.2% for the diagnosis of colon cancer, respectively. Laser-induced fluorescence (LIF) spectrum of colon is of use in the diagnosis of colon cancer.

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