Protoporphyrin derivatives--the use in localization of neoplasmas by titanium laser-induced fluorescence technique
Kwaśny, M.; Mierczyk, Z.; Fiedor, P.; Rowiński, W.; Socha, K.; Graczyk, A.; Domaniecki, J.; Mazurek, A.P.
Acta Poloniae Pharmaceutica 54(2): 123-128
1997
ISSN/ISBN: 0001-6837 PMID: 9415203 Document Number: 475599
Examples of in vivo detection of skin neoplasmas (Mercl, melanoma) and breast carcinoma using laser induced fluorescence (LIF) and bis-1[1-alanylo-N]-ethylodeuteroporphyrin (Ala-PP) are described in this study. Photosensitizer, wave titanium laser and standard CCD camera coupled to vision amplifier enable precise neoplasm imaging, Ala-PP retention monitoring and further photodynamic therapy (PDT).