Compensatory rehabilitation processes and instrumental reflexes in rats after neurotoxic lesions in the inferior olive
Fanardzhian, V.V.; Oganesian, E.A.; Melik-Musian, A.B.; Papoian, E.B.; Gevorkian, O.V.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 84(8): 719-727
1998
ISSN/ISBN: 0869-8139 PMID: 9845888 Document Number: 494229
Training and recovery of instrumental equilibrium reflexes are impossible after total neurotoxical destruction of the inferior olive in rats. Motor deficits and compensatory rehabilitation processes in rats following 3-acethylpyridine treatment and high transection of the dorso-lateral funiculus of the spinal cord are closely correlated with the degree of the inferior olive destruction. The data obtained revealed an improvement in the motor disturbance and a stabilising of the instrumental reflexes in the rats with subtotal lesion of the inferior olive.