The use of neomycin in the treatment of methylmalonic aciduria
Snyderman, S.E.; Sansaricq, C.; Norton, P.; Phansalkar, S.V.
Pediatrics 50(6): 925-927
1972
ISSN/ISBN: 0031-4005 PMID: 4636459 Document Number: 49375
Neomycin by mouth reduced methylmalonic acid in urine and plasma of a girl 5 years old with methylmalonic aciduria. It is thought that the effect of the antibiotic on the gastrointestinal bacteria reduced production of propionate, the immediate precursor of methylmalonic acid.
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