Effect of rotundine on gastric acid and pepsin activity in rats
Zhou, M.; Li, X.; Geng, L.; Qu, C.; Peng, S.
Zhongguo Zhong Yao Za Zhi 23(5): 301
1998
ISSN/ISBN: 1001-5302 PMID: 11601318 Document Number: 493137
A test was made on the effect of rotundine on the secretion of gastric acid and pepsin activity in rats. Compared with the control group, rotundine(> or = 17.1 mg/kg) inhibited gastric acid and decreased secretion of gastric juice(P < 0.01), but had no influence on pepsin activity. There was a negative relationship between total acidity and pH of gastric juice (r = -0.9818).
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