Drug clinics. how i treat various metabolic diseases treated by a drug intervention that targets the intestine
Scheen, A.J.
Revue Medicale de Liege 53(11): 646-650
1998
ISSN/ISBN: 0370-629X PMID: 9887653 Document Number: 492498
Besides the classical dietary regimen, it is possible to use specific pharmacological approaches, targeted at the intestine, in order to treat some metabolic disorders. Three approaches will be described: anionic resins for treating hypercholesterolaemia, alpha-glucosidase inhibitors for treating diabetes mellitus and reactive hypoglycaemia, and intestinal lipase inhibitors for treating obesity. All these drugs are based on original concepts, but their clinical use is often limited by the occurrence of digestive side-effects. The latter may generally be reduced by progressive and individual titration of the dosage of each drug and/or by following an appropriate diet.