Structural basis for the regulation of the neuronal sensitivity

Babmindra, V.P.; Novozhilova, A.P.; Bragina, T.A.; Kreĭchman, G.S.; Miasnikova, O.E.; Zhilinskaia, N.T.; Kolla, G.V.; Babmindra, V.P; Novozhilova, A.P; Bragina, T.A; Kreichman, G.S; Miasnikova, O.E; Zhilinskaia, N.T; Kolla, G.V

Home

>

Node

>

Subnode

Structural basis for the regulation of the neuronal sensitivity

Babmindra, V.P.; Novozhilova, A.P.; Bragina, T.A.; Kreĭchman, G.S.; Miasnikova, O.E.; Zhilinskaia, N.T.; Kolla, G.V.

Morfologiia 114(6): 22-27

1998

ISSN/ISBN: 1026-3543

PMID: 10763482

Document Number: 491756

Using light and electron microscopy structural bases for intracellular, extracellular and integrative regulation of synaptic efficiency and neuron sensitivity were established in rat sensomotor cortex. Intracellular regulation is realized basically through modulation of postsynaptic components of the synapse, while extracellular one is provided by synaptic endings of "recurrent" axons on GABA-ergic relay and interneurons. Integrative regulation is realized by means of concentration of similar axonal terminals in restricted cortical area and arrangement of "neuromediatory" pool.