Is it possible to consider intranuclear DNA imaging analysis as a new parameter in the staging of colorectal cancer?
Midiri, G.; Giovagnoli, M.R.; Tesoriere, A.; Giarnieri, E.; Covotta, L.; Bertolotti, A.; Vecchione, A.; Di Paola, M.
Il Giornale di Chirurgia 19(1-2): 9-12
1998
ISSN/ISBN: 0391-9005 PMID: 9567488 Document Number: 490442
Intranuclear DNA imaging may be considered as a marker of the biological behaviour of neoplasias. However, some questions fundamentally related to the interpretation of cytometric data, to the correlation with other histomorphological parameters and to tissue sampling concerning staging and prognostic evaluation of colon cancer patients are still unsolved. A way to solve this problem may be to perform multiple full thickness samplings.
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