Diagnosis using monoclonal antibody imaging in the clinical follow-up of colorectal cancer
Campos Villarino, L.M.; Pajares Vinardell, M.; Freire Macias, J.M.; Vale Gonsalves, E.I.; Millán Núñez-Cortés, J.; Senra Varela, A.
Anales de Medicina Interna 8(8): 377-381
1991
ISSN/ISBN: 0212-7199 PMID: 1768746 Document Number: 385538
A total of 44 patients with a range of ages between 34 and 72 were studied by immunoscintigraphy. They have surgical treatment for colon and rectum carcinomas. The immunoradiotracer used was a cocktail of F(ab')2 monoclonal-antibodies anti-CEA and CA 19.9. Planar images were obtained 4th, 6th, and 10th days postinjection. In some cases we used digital subtraction of image. Both CEA and CA 19.9 tumor markers were measured in patients serum. The method shows a global high sensitivity (88%), and specificity (92%).