Effect of solution pH on the reactivity of the isolated segment of the rat mesenteric artery subjected stretching of various degree
Iartsev, V.N.; Karachentseva, O.V.; Dvoretskiĭ, D.P.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 84(8): 775-782
1998
ISSN/ISBN: 0869-8139 PMID: 9845895 Document Number: 490252
Experiments on the rat mesenteric artery's segments at different degrees of its stretching showed no influence of acidosis or alkalosis on the vessel wall tension within a wide range of pH (7.8-6.6). Acidification of the solution (7.0 or 6.6) inhibited the vessel response to noradrenaline or electrical field stimulation (EFS). On the contrary, the acidification potentiated a constriction caused by the EFS at a high level of vascular tone.