New means for the prophylaxis of colon cancer with the use of beta-glucuronidase inhibitors
Pliss, G.B.; Vlasov, N.N.; Anikin, I.V.
Voprosy Onkologii 44(1): 68-73
1998
ISSN/ISBN: 0507-3758 PMID: 9578735 Document Number: 489546
Experiments involving the use of 1,2-dimethylhydrazine-induced colonic tumors in rats showed long-term treatment with a newly synthesized drug EDE-10g to inhibit an enzyme of enteric beta-glucuronidase, to suppress carcinogenesis and to prolong lifespan of animals.