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Effect of a bioactive food supplement from selenium enriched baker's yeast autolysate on the status of the intestinal barrier in rats with anaphylaxis

Golubkina, N.A.; Gmoshinskiĭ, I.V.; Zorin, S.N.; Danilina, L.L.; Chistiakov, A.V.; Mazo, V.K.

Voprosy Pitaniia 1998(3): 18-22

1998

ISSN/ISBN: 0042-8833
PMID: 9752666
Document Number: 488098
Rat's intestinal barrier permeability disturbed in consequence of intestinal anaphylaxis reaction was almost completely normalized in animals fed with baker's yeast autolysate "Vitasil" enriched with selenium on a level of 3 mg Se/day during 29 days. These rats showed in comparison to Se-unsupplemented animals a significant elevation of Se level in red blood cells and plasma together with a decrease of intestinal mucosal TCA-soluble thiol compounds. Urinary Se excretion was significantly elevated in comparison to unsensitized rats both in Se-supplemented and unsupplemented animals with anaphylaxis. It's concluded that "Se-Vitasil" may be successfully used in antioxidative therapy of food allergy, malabsorption, inflammatory bowel diseases and intestinal infection.

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