Nitric oxide in dengue pathology
Rodriguez-Ortega, M.
Acta Cientifica Venezolana 49(Suppl 1): 8-12
1998
ISSN/ISBN: 0001-5504 PMID: 10030048 Document Number: 485261
Nitric oxide (NO) is a multifunctional molecule that is involved in citotoxic as well as citoprotective processes, it's synthesis is highly regulated by the cell because an alteration in NO production is associated with a variety of pathologies, such as Septic, Anaphylactic and Hemorrhagic Shock. The clinical feature of dengue virus infection has a spectrum that goes from mild, dengue fever, to a severe disease, dengue hemorrhagic fever/dengue shock. Here, some evidences are discussed that links NO with the pathology of the severe disease cause by dengue virus.
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