Antifolate-resistant malaria infections in Mpumalanga

Durrheim, D.N.; Sharp, B.L.

South African Medical Journal 88(4): 469

1998


ISSN/ISBN: 0256-9574
PMID: 9594995
Document Number: 484374
In response to a letter by L. Birkholtz et al. [South African Medical Journal (1998) 88, 58-60] on the prevalence of mixed species and antifolate-resistant malaria infections in Mpumalanga, South Africa, the correspondents comment on the use of a poorly-defined and small sample of Plasmodium falciparum malaria infections in the pyrimethamine resistance analysis and highlight the need for ongoing population-based drug efficacy studies to inform rational malaria drug policy in South Africa.

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