Clinical studies on renal pelvic and ureteral carcinoma
Akino, H.; Ishida, H.; Ito, Y.; Tanase, K.; Isomatsu, Y.; Muranaka, K.; Mori, H.; Kanamaru, H.; Okada, K.
Hinyokika Kiyo. Acta Urologica Japonica 43(4): 257-262
1997
ISSN/ISBN: 0018-1994 PMID: 9161851 Document Number: 482784
We reviewed 40 patients with renal pelvic and/or ureteral transitional cell carcinomas, consisting of 24 males and 16 females with a mean age of 65 years. The histopathological stage of surgically removed specimen was pTa in 6 patients, pT1 in 7, pT2 in 5, pT3 in 11 and pT4 in 6. Three patients with Tis and 2 with T3 did not undergo surgery. Of 35 patients pathologically examined, lymphatic and venous invasions were detected in 22 (63%) and 16 (46%), respectively, and were associated with pathological stage and grade. Overall the 5-year actuarial survival rate was 57.1%. Tumor staging and vascular invasion had a prognostic significance on the treatment outcome, but not metachronous or synchronous bladder cancer, identified in 55% of the patients. Adjuvant chemotherapy appeared to improve the survival of the patients with tumors pT2 or higher, grade 3 or vascular invasion without metastases.