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Plasminogen tissue activator and plasminogen tissue inhibitor in type Ii diabetes

Rość, D.; Drewniak, W.; Kotschy, M.; Graczykowska-Koczorowska, A.; Raukuć, D.

Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 2(7): 24-25

1997

ISSN/ISBN: 1426-9686
PMID: 9296893
Document Number: 481916
The aim of study was the evaluation of tissue plasminogen activator (t-PA) and its inhibitor (PAI-1) in the II type diabetes on the base of the common fibrinolytic system tests as euglobulin lysis time (ELT) and the concentration of fibrin/fibrinogen products (FDP). The studies were performed in 21 outpatients suffering of II type diabetes aged 38-65 (median 56.0) years treated with diet and sulphonylcarbamide derivates. The control group contained 18 healthy persons aged 33-65 (median 42.0) years. In the blood the following determinations were performed: antigen of t-PA and PAI-1, ELT and FDP. In the blood of patients with II type diabetes increased. t-PA Ag and PAI-1 Ag concentrations were observed.

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