Helicobacter pylori and intestinal metaplasia of gastric mucosa
Satarkar, R.P.; Sawant, P.; Nanivadekar, S.; Shroff, C.
Indian Journal of Gastroenterology Official Journal of the Indian Society of Gastroenterology 16(1): 16-17
1997
ISSN/ISBN: 0254-8860 PMID: 9167374 Document Number: 480473
The role of Helicobacter pylori in stomach carcinogenesis is currently under study. H pylori-related chronic gastritis leading to dysplasia or intestinal metaplasia (IM) especially of the colonic type is postulated as one of the mechanisms. We studied 120 patients with or without H pylori infection to determine the frequency of occurrence of IM in the stomach. IM was found in 16.6% of patients; most cases had the small intestinal type, which is not known to have a malignant potential. There was no relation between H pylori infection and development of IM. H pylori infection leading to IM does not appear to be a factor in the genesis of carcinoma stomach in our population.