Mammary carcinoma with osteoclastlike giant cells cytologically mimicking benign breast disease. A case report
Shabb, N.S.; Tawil, A.; Mufarrij, A.; Obeid, S.; Halabi, J.
Acta Cytologica 41(4 Suppl): 1284-1288
1997
ISSN/ISBN: 0001-5547 PMID: 9990259 Document Number: 478042
BACKGROUND: Mammary carcinoma with osteoclastlike giant cells (OCLGCs) is a rare tumor. Few reports on the fine needle aspiration (FNA) findings are available. This case had cytologic findings overlapping with benign breast disease. CASE: A 50-year-old woman presented with multiple masses in her right breast and a 2-cm right axillary lymph node. Cytologic scrapings and FNA of the same breast mass showed large cohesive, two-dimensional epithelial cells with a uniform distribution of small, bland nuclei. Discohesion, single cells with features of malignancy, cytologic atypia and mitosis were lacking. Many OCLGCs were present. CONCLUSION: The cytologic features of this rare type of breast carcinoma need to become familiar to pathologists to avoid a false negative diagnosis.