The role of strontium-89 systemic radiotherapy in the management of osseous metastases from prostate cancer
Soffen, E.M.; Greenberg, A.; Baumann, J.; Corn, B.W.
Techniques in Urology 3(2): 76-80
1997
ISSN/ISBN: 1079-3259 PMID: 9297766 Document Number: 475847
Strontium-89 systemic radiotherapy can play a significant role in the palliation of symptomatic osseous metastases from prostate cancer. Given as a single injection, strontium's affinity for osteoblastic activity draws it to all sites of osseous involvement simultaneously. The metastases are bathed with beta-particles whose short range in tissues spares the surrounding normal structures. This article will review the rationale, physiology, and patient selection criteria for its use. Approximately 80% of patients will respond to treatment as documented by the authors experience and by a review of the literature.