Serial bone scintigraphy for assessing the effectiveness of treatment of osseous metastases from prostatic cancer
Langhammer, H.; Sintermann, R.; Hör, G.; Pabst, H.W.
Nuklearmedizin. Nuclear Medicine 17(3): 87-91
1978
ISSN/ISBN: 0029-5566 PMID: 568257 Document Number: 132675
130 serial bone scintigrams were performed to evaluate the course of skeletal metastases under treatment in 36 patients with prostatic cancer. During a successful treatment scintigraphic controls revealed a significant decrease of the metastatic 99mTc-diphosphonate uptake in 14 patients and sometimes even a complete normalization of the skeletal radioactivity distribution, whereas a progression characterized by an increased multifocal radioactivity concentration was registered in 16 patients indicating the failure of the initiated therapy. Based on these results of follow-up studies scintigraphic bone imaging can be recommended for the assessment of the effectiveness of on-going therapy of skeletal metastases.